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Handbook of polyester drug delivery system (Record no. 494761)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02199nam a22001937a 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 210826b |||||||| |||| 00| 0 eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| ISBN | 9781681176925 |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 615.2 |
| Item number | HAN |
| 245 ## - TITLE STATEMENT | |
| Title | Handbook of polyester drug delivery system |
| Statement of responsibility, etc | edited by Jakub Sarto |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) | |
| Place of publication | New York |
| Name of publisher | Scitus Academics LLC |
| Year of publication | 2018 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Number of Pages | viii, 300 p. |
| Other physical details | ill. |
| Dimensions | 23 x 15 cm. |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE | |
| Bibliography, etc | Includes bibliographies and index |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc | Polymers that can degrade into biologically compatible components under physiologic conditions are advantageous for the preparation of drug delivery systems (DDS). The use of biodegradable polymers precludes the need for retrieval at the conclusion of the dosing regimen, thereby avoiding the potential complications associated with the use of non-degradable systems. Homopolymers and copolymers, obtained from glycolide, lactide and caprolactone and trimethylene carbonate (TMC), are the most commonly considered drug delivery vehicles. However, there are still few implantable drug delivery systems obtained from biodegradable polymers. Attachment of drugs to high molecular weight polymers can significantly improve both tumor targeting and therapeutic efficacy due to the enhanced permeability and retention effect observed in tumour tissue. However, the commercial availability of well-defined water-soluble polymeric systems with narrow polydispersities that are biocompatible, nontoxic, and nonimmunogenic is rather limited. Even with the progress of novel materials, polyesters still endure at the controls of drug delivery technologies. The book provides comprehensive information of polyester drug delivery systems that covers a wide-ranging of materials design, manufacturing techniques, and applications. Polyglycolide (PGA) was one of the first biodegradable synthetic polymers investigated for biomedical applications and was synthesised for the first time in 1954. In the beginning, it was not considered for biomedical applications because of its thermal and hydrolytic instability. However, the ability to degrade inside the human body became a great advantage. |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical Term | Medicine |
| Topical Term | Polyesters |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Sarto, Jakub |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | English Books |
| Withdrawn status | Lost status | Damaged status | Not for loan | Home library | Current library | Shelving location | Date acquired | Full call number | Accession Number | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Anna Centenary Library | Anna Centenary Library | 5TH FLOOR, A WING | 21.03.2021 | 615.2 HAN | 617844 | 26.08.2021 | English Books |